News of the week 2

News of the Week 2

The mebutate de ingenol (ingenol-3-angelato) is a secondary metabolite of plant found in the sap of the species Euphorbia. The US Food and Drug Administration UU and the European Medicines Agency (EMEA) have approved a drug gel formula for the topical treatment of actinic keratoses under the Picato Brand.

                                     

"Phyton aims to offer a technology based on plant cell culture that would allow the sustainable and scalable GMP production of mebutate from ingenol, its precursor ingenuity and other plant secondary metabolites with a similar mode of action," said Kai Schuette, Managing Director Of Phyton Biotech GmbH. "We are delighted with the results so far and the development of additional IP to improve the value of our PCF® technology."

"The invention disclosed in the patent application offers, for the first time, suspension cell cultures adapted for the mass production of mebutate de ingenol which offers a potential alternative for the commercial scale production of this difficult to manufacture molecule," said the doctor Gilbert Gorr, scientific director and head of Research and Development. "This approach is another exciting example of the ability of plant cell cultures as a possible delivery solution."